Does age affect retinal drusen, pigmentary abnormalities, and overall macular degeneration? In the Beaver Dam Eye study, 4926 patients from age 43 to 68 were studied using stereoscopic color fundus photography to answer this question.
Overall, the Beaver Dam Eye study is a landmark trial because it demonstrated the association between AMD and age, and was one of the first large scale prevalence studies for the disease. This association was deemed a “substantial public health problem” that previously had not been realized.
- Data indicated that individuals 75 years of age or older commonly had signs of AMD
- Identified features included large drusen, soft indistinct drusen, abnormal retinal pigmentation, exudative macular degeneration, and geographic atrophy
- 95.5% of the population studied had at least one drusen in the macula of one of their eyes.