by Julie Yoo
From how we pay for healthcare to how we experience healthcare, this deck shares key changes happening in the healthcare system -- thanks to core infrastructure, novel business models, and access points. Where are the opportunities and approaches for startups in this space?
watch this talk
read the talk
with Jad Naous
As a startup, it's hard to negotiate customer contracts because you're not yet established or trusted in the marketplace, so customers are taking on the risk. Many founders therefore make the mistake of being overly accommodating during initial contract negotiations -- when they should be thinking more systemically about the risk/ reward tradeoffs. Drawing on the expertise of lawyers, founders, and CROs on what they learned about winning the deal without taking on contractual risk, this post shares 16 important sales contract clauses... and how to approach each.
read the list
with Sonal Chokshi et al
Introducing our new podcast, 16 Minutes, a short news podcast where we cover the top headlines of the week, the a16z Podcast way -- why are these topics in the news; what’s real, what’s hype from our vantage point; what are our experts’ quick takes on the trends involved; and where does tech come in? Subscribe in your favorite app or catch up here:

Episode 1: 
  • Neuralink & brain-computer interfaces -- with Vijay Pande
  • TikTok video influencers & the AI-driven model -- with Connie Chan
  • FaceApp & privacy beyond national security -- with Joel de la Garza
  • iHeart Radio & direct listings -- with Jamie McGurk
Episode 2:
  • mobile malware & post-perimeter security -- with Martin Casado
  • drug pricing proposals, lay of the land, what is a medicine -- with Jorge Conde and Jay Rughani
Episode 3:
  • Fortnite, esports, gaming, social, & the future of entertainment -- with Andrew Chen and D'arcy Coolican
Episode 4:
  • the opioid crisis: who, where, how, & more -- with Jorge Conde and Vijay Pande
with Connie Chan, Kurt House, John Thompson, and Hanne Tidnam
The exploration and mining of metals has long driven human civilization, and that now includes cobalt -- thanks to the need for batteries in phones, electric cars, and more. How is technology changing how we find it, mine it, gather data about it? This episode of the a16z Podcast goes beneath the surface.
listen to this episode
with Jorge Conde and David Ulevitch
In early-stage bio companies, the 10x research associate is responsible for painstakingly optimizing lab protocols, running complex experiments, and analyzing reams of data generated by those experiments. They're the ones who ensure that academic research can be reliably replicated in the startup lab environment, and that the underlying science can be industrialized into a robust and scalable platform. read more

For many enterprise startups, the 10x customer is hiding in plain sight -- which means they can go bigger sooner than they think, and each rung on the ladder gets easier. After establishing a set of customers at a consistent price point, it’s almost always possible to get a customer at 10x the scale (without major product or go-to-market shifts). read more 

This is the monthly edition of the a16z newsletter, which features content and resources curated and produced by Andreessen Horowitz. You can catch up on past issues here -- or sign up for our other newsletters; we now have *new* editions dedicated to topics like bio and fintech!

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Andreessen Horowitz · 2865 Sand Hill Road, Suite 101 · Menlo Park, CA 94025 · USA