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April 2016
Institute for Clinical Evaluative Sciences
At a Glance: Monthly research findings straight to your inbox

Statins shown to be safe in generic form for high-risk coronary patients
Jackevicius CA, Tu JV, Krumholz HM; Austin, PC, Ross JS, Stukel TA, Koh M, Chong A, Ko DT. Comparative effectiveness of generic atorvastatin and Lipitor® in patients hospitalized with an acute coronary syndrome. J Am Heart Assoc. 2016; 5:e003350.

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Ontarians' unhealthy behaviours cost $89.4 billion between 2004 and 2013
Manuel DG, Perez R, Bennett C, Laporte A, Wilton AS, Gandhi S, Yates EA, Henry DA. A $4.9 Billion Decrease in Health Care Expenditure: The Ten-Year Impact of Changing Smoking, Alcohol, Diet and Physical Activity on Health Care Use in Ontario. Toronto, ON: Institute for Clinical Evaluative Sciences; 2016.

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Adult prescriptions for ADHD drugs more than doubled in five years, but access uneven across Canada
Ontario Drug Policy Research Network. Drugs used in the management of attention deficit hyperactivity disorder in adults: a drug class review. Accessed April 25, 2016 at

Youtube Video Interview
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Poor contraceptive practices are leading to pregnancies in users of isotretinoin, a drug that causes birth defects
Henry D, Dormuth C, Winquist B, Carney G, Bugden S, Teare G, Lévesque LE, Bérard A, Paterson JM, Platt RW, for the CNODES (Canadian Network for Observational Drug Effect Studies) Investigators. Occurrence of pregnancy and pregnancy outcomes during isotretinoin therapy. CMAJ. 2016; Apr 25 [Epub ahead of print].

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Dementia patients with multiple physicians or in long-term care at risk of medication conflict

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