logo 220 Summer  Newsletter 2018
We're excited to announce our upcoming conference Systemic Effects of Metal Exposure in Clinical Practice: Protecting Patients and Optimising Outcomes organised together with the British Society for Ecological Medicine. As a memorial conference for Prof Vera Stejskal, we'll be welcoming colleagues from near and far to reflect the international reach of her work. More details below.
IAMOT UK are also holding a conference next weekend in London. IAOMT is an excellent organisation comprised of dental practitioners and health professionals that promotes the goal of safe, bio-compatible dental care.
MELISA and BSEM conference: London, 16th November
We are delighted to welcome global experts in the field of metal toxicity and allergy, as well as surgeons and researchers offering practical methodologies and recommendations to improve clinical outcomes. Speakers include Prof Chris Exley, well known in the field of aluminium toxicology; Mr Simon Ellis, a renowned orthopaedic surgeon; and Dr Scott Shroeder, who will be talking about the extraordinary recoveries he observes when implants are removed from metal allergic patients. The full programme and details for registration are here.
Exhibitors wishing to attend please email us on info@melisa.org for details about the opportunity.
Autoimmune disease development and metal exposure from medical devices linked
IAOMT has written a comprehensive review of the link between autoimmune disease and metal exposure. The article also features the research of the late Prof. Stejskal, who chronicled cases of recovery after safe removal of medical and dental implants and devices containing metal. 

Researchers have identified that autoimmune disease can be caused by a combination of: 1) genetic components, and 2) metals (including those used in medical and dental implants and devices), pharmaceutical drugs, pollen, infectious agents, molds, and food allergies (such as gluten). 

Diagnosing and treating alopecia caused by metal allergy
This fascinating article describes treating patients with alopecia areata by removing exposure to environmental and dental metals to which patients are allergic. Discovering the link between severe alopecia areata and metal allergy was coincidental. An alopecia patient (pictured below) lost all her recently regrown hair after a flu vaccine containing thimerosal. Mercury allergy was diagnosed and after the removal of mercury containing fillings and avoidance of further vaccination: the patient was cured of alopecia. Other cases with allergies to nickel, chromium and house dust mites are also presented. ​
Higher prevalence of titanium allergy than previously supposed
This new article about titanium dental implant allergy shows a 6.3% prevalence of titanium allergy. Pretty high for a metal that is considered to be completely bio-compatible! The study states that although titanium allergy is uncommon, pre-implant dental patients with a history of dermal reactions to metals should be examined more fully. Interestingly, the study looked at other metals too. It recorded the highest rates of allergy in 270 patients being to inorganic mercury and palladium. Higher reactions than to nickel, which is generally considered to be the most allergenic metal.
Hypersensitivity of growing concern in spinal surgery
We're all too aware of the problems with metal-on-metal (MOM) hip implants, but have a look at this recent article about MOM implants in spinal surgery. 2/5 patients needed revision surgery (to titanium) 2 years after having a MOM facet replacement. Initially, they were pain free but after 2 years pain returned and hypersensitivity to cobalt was diagnosed. The authors, quite rightly suggest that caution is needed when implanting these new devices. Perhaps metal allergy testing would be a good idea as well

Is metal implant choice driven by cost and convenience rather than bio-compatibility?
Pectus excavatum (PEx) is one of the most common congenital chest wall deformities and a metal Nuss bar is used to correct it. This recent article discusses a case of allergy and goes on to say that "Before the Nuss procedure, patients should be evaluated for allergies to jewelry, orthodontic braces, metal buttons on clothing and also signs and symptoms of atopy (allergic rhinitis, eczema, asthma)."
Worryingly, it also mentions that the more bio-compatible alternative - titanium - is much more expensive (4-5 times more) and more complicated than the steel option.

MELISA Diagnostics
Email info@melisa.org
Phone +44 20 8133 5166
Web www.melisa.org
MELISA Testing
Exposure to metals through dental fillings and implants, joint prostheses, environmental pollutants and medication can create health problems in hypersensitive individuals. Metals may trigger Type IV cell mediated allergies. MELISA is a blood test which can identify which metals, that person is exposed to, can cause health problems. MELISA testing has been developed to test for Lyme disease and for allergy to a small number of foods.

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MELISA Diagnostics · Warren Place · Birch Vale · Cobham, Surrey KT11 2PX · United Kingdom

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