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Winter 2016


Continued full accreditation awarded by AAALAC

aaalac logoThe results from the site visit conducted June 6-10, 2016 to evaluate our Animal Care and Use Program are in, and we are pleased to report that continued Full Accreditation has been awarded by the AAALAC International Council. Thanks to everyone involved for making this a successful site visit. Congratulations, and keep up the good work! Additional information about AAALAC International can be found on their website.

USDA inspection results

USDA LogoThe United States Department of Agriculture (USDA) Animal and Plant Health Inspection Service conducted an unannounced inspection of housing facilities and animal use locations at the Ohio Agricultural Research and Development Center (OARDC) in Wooster on December 6, 2016. We are pleased to report that no citations were identified. Congratulations!

Office hours and workshops available at the Research Commons

Research CommonsDo you need help preparing your IACUC protocol, navigating e-Protocol, organizing for semiannual facility inspections or responding to inspection outcomes? Do you want to learn more about the IACUC review process, policies or best practices? Starting in February 2017, the Office of the Attending Veterinarian (OAV) and the Office of Responsible Research Practices (ORRP) will hold office hours at the Research Commons (3rd floor, 18th Avenue Library, 175 W. 18th Avenue).

Angela Phillips, OAV protocol consultant, will be available to help you prepare your IACUC protocol using e-Protocol and obtain veterinary consultation prior to the IACUC review. Melinda Bruns, quality improvement specialist from ORRP's IACUC office, will provide guidance with IACUC policies, the protocol review cycle, facility inspections and post-approval activities.

Schedule a consultation. Use the drop-down menu to select the service “Animals in Research (IACUC)” and indicate with whom you wish to meet.
In addition, three workshops will be hosted at the Research Commons: These workshops are a great resource for investigators, post-docs, graduate and undergraduate students, lab managers listed on an IACUC protocol and new researchers interested in learning more about the Animal Care and Use Program.

Register by visiting the Research Commons events webpage or click on the title of the workshop listed above.

More information about working with animals in research can be found on the Animals in Research webpage

Thank you for your continuing efforts to improve our Animal Care and Use Program.


The AALAS technician certification program recognizes professional achievement in laboratory animal science at three levels: Assistant Laboratory Animal Technician (ALAT), Laboratory Animal Technician (LAT) and Laboratory Animal Technologist (LATG).

Congratulations to the following ULAR staff who have passed American Association for Laboratory Animal Science (AALAS) certification exams:
  • Christin Gould, ALAT
  • Megan Fleming, ALAT
  • Melinda Stimpson, ALAT
  • JoBeth Helmig-Mason, ALAT
  • Andreanna Pavan, LAT 
Also, congratulations to the Ohio State representatives who attended the 2016 National AALAS Meeting in Charlotte, North Carolina, and presented eight posters.

Zoonotic fact sheets for working with pigs

When working with animals, you should be familiar with diseases that could be transferred between animals and humans. Below is a list of some of the causative agents that you may be exposed to when working with pigs:
  • Yersiniosis
  • Toxoplasmosis
  • Leptospirosis
  • Salmonella
  • Influenza
  • Cryptosporidosis
  • Campylobacter
Fact sheets with information about these specific agents and agents for other species are available on the Office of Environmental Health and Safety website. Check back frequently as additional fact sheets are being uploaded for other species.

IACUC semiannual inspection summary

For the July to December 2016 semiannual inspection reporting period, 77 percent of the rooms inspected had no findings at the time of the inspection. Congratulations, and thank you for your hard work in maintaining the 393 rooms that had no findings.


Policy updates

All policies developed by the Ohio State IACUC to assist investigators and staff with their research are available on the IACUC Policies webpage. Policies and SOPs are reviewed on a regular basis to ensure that they continue to meet regulatory requirements.
Revised–Autoclave Verification and Validation for Survival Surgery Equipment: The policy describes the requirements to ensure verification and validation when an autoclave is the selected method of sterilization for survival surgery equipment or instruments. A chemical control indicator must be present on the outside and inside of surgical packs prior to autoclaving to confirm adequate steam penetration. Items must be resterilized prior to use if the chemical control indicators fail to reach the required autoclave cycle temperature, within one year from the date of initial sterilization or if the outer covering is compromised. View the revised policy
Revised–CO2 Euthanasia of Rodents: The policy was reviewed, a definition was added to define rodents and the previous policy information was transferred to the new format for IACUC policies. Note that chambers should be inverted and cleaned between groups. View the revised policy

Revised –Rodent Survival Surgery: The policy was reviewed and revised to provide clarifications on the procedures for maintaining sterility of instruments. If instrument tips contact a non-sterile surface, a new sterile pack of instruments must be opened, or alternatively, instrument tips must be wiped clean of organic material and placed in a hot bead sterilizer for 10-20 seconds (at 240-270°C) to maintain aseptic technique.
When performing multiple rodent survival surgeries, the same set of instruments can be used for up to five animals if sterility of the instruments is maintained. Instrument tips must be wiped clean of organic material using sterile supplies (e.g., wipes and sterile water/saline) and placed in a hot bead sterilizer for 10-20 seconds (at 240-270°C) or soaked in 70 percent isopropyl alcohol for two minutes between surgeries. Remember, gloves must be changed or properly disinfected between animals or if torn.

For additional details regarding aseptic technique refer to the Best Practices for Rodent Survival Surgery. View the revised policy.


Remember to click “Forward” and “Submit”

In e-Protocol, each submission (protocol, amendment or annual review) has a submission workspace. When a PI has finished creating or editing, there is always one more step that must be taken—sending that submission to a reviewer. To do this, a list of action links on the submission workspace can be found under “My Activities.”  The type of submission and the stage in the review process will determine which action links display. Here is a quick list of actions available:
Activities Table


Tip #1: What do I do if I have an annual review and an amendment due at the same time?

Submitting an annual review (AR) and an amendment (AM) are separate functions in the e-Protocol system. If you have an amendment pending or in review, you can submit an annual review at the same time (or if you have an annual review pending or in review, you can submit an amendment at the same time).

Tip #2: Do I need an IBC protocol in addition to my IACUC protocol or amendment?

Are you submitting an IACUC protocol or amendment that includes inserting recombinant or synthetic nucleic acids in animals and/or working with microorganisms pathogenic to human, plants or animals? If so, you will want to ensure your work is also covered by the Institutional Biosafety Committee (IBC). Starting the IBC process before or at the same time you start your IACUC protocol or amendment could prevent delay in receiving IACUC approval.

Tip #3: How do I add new personnel to an IACUC protocol?

My ActivitiesBefore new personnel can be added to a protocol, they must register in e-Protocol and complete all the training requirements. If a study team member’s name is not visible in the drop down list for adding personnel, it means that the person is not yet registered in the e-Protocol system.
Adding new study team members is a two-step process. Any study team member can see and click the link “Propose Study Team Change” and add new personnel, but only the principal investigator can see and click the link “Submit Study Team Change.” The change in study team is not complete until the investigator submits it.

Tip #4: Do I need to update the "Justification for Number of Animals Requested" section?

When submitting an amendment to increase your animal numbers, be sure to make those changes in the tables listed in the "Justification for Number of Animals Requested" section of e-Protocol. The e-Protocol system uses those tables to calculate the number of animals approved in the system. The information is not taken from the narrative provided. Remember that the justification narrative should reflect or match the number provided in the tables.


Get to know ORRP director Kim Toussant

Kim Toussant was appointed the director of the Office of Responsible Research Practices (ORRP) in January 2016. Prior to joining ORRP, Kim was the administrative director of the Center for Clinical and Translational Science (CCTS) and continues in the role of co-director of the CCTS Regulatory Program. She previously held the position of clinical research manager for the National Institutes of Health funded Women’s Health Initiative and the Osteoarthritis Initiative, as well as industry-sponsored pharmaceutical clinical trials. Kim holds masters degrees in public administration and in business operational excellence from The Ohio State University. She received a Lean Six Sigma Black Belt certification from the Fisher College of Business and research administrator certification from the Research Administrators Certification Council.
  • Continued full accreditation awarded by AAALAC
  • USDA inspection results
  • Office hours and workshops available at the Research Commons
  • Congratulations
  • Zoonotic fact sheets for working with pigs
  • Policy updates
  • Reminders
  • E-Protocol tips
  • Staff profile
Meeting planner

Upcoming IACUC meeting dates

December 16, 2016
January 20, 2017
February 17, 2017
March 17, 2017

Meetings begin at
12:30 p.m.

Additional information about submission deadlines can be found on the IACUC meetings webpage.

ULAR training sessions

Facility Introduction and Mouse Overview
2016-2017 dates and times:

December 27 (1 p.m.)
January 12 (10 a.m.)
January 24 (1 p.m.)
February 9 (10 a.m.)
February 28 (1 p.m.)
March 9 (10 a.m.)
March 28 (1 p.m.)
Rodent Survival Surgery
2016-2017 dates and times: 

December 20 (10 a.m.)
January 17 (10 a.m.)
February 21 (10 a.m.)
March 21 (10 a.m.)

Class sizes are limited to 15 registrants.
To register, call
614-292-5094, email or complete the training request form.
Individual sessions
may be arranged for protocol-specific techniques by completing the training request form or by emailing

Office of
Research Units

© 2016 The Ohio State University – Office of Research
Office of Responsible Research Practices – Institutional Animal Care and Use Committee
Research Administration Building, 1960 Kenny Road, Columbus, OH 43210
Phone: 614-688-8457 | Fax: 614-688-0366 | Email the IACUC

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