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Fall 2016

PROGRAM NEWS

AAALAC site visit completed in June 2016

aaalac logoThe AAALAC International site visit was conducted June 6-10, 2016, to evaluate Ohio State’s Animal Care and Use Program. Many positive commendations were made by the site visit team. The site visit team will provide a report to the AAALAC International Council on Accreditation in September. The Council will then determine Ohio State's accreditation status. Thanks to everyone involved in our Animal Care and Use Program for making this a successful visit. Congratulations, and keep up the good work! Additional information on AAALAC International can be found on their website.

USDA inspection results

USDA LogoRepresentatives from the United States Department of Agriculture (USDA) Animal and Plant Health Inspection Service arrived on campus July 11, 2016, to conduct their annual, unannounced inspection. Inspectors spent four days visiting animal use locations and housing facilities and reviewing selected protocols and IACUC documents. We are pleased to report that no citations were identified. Thank you to all who were able to meet with the inspectors on short notice.

Employee accident reporting procedures

When a workplace incident or accident occurs, it should be reported to a supervisor, and an Employee Accident Report should be completed. If an employee feels he/she may have been exposed to a hazardous agent, Environmental Health and Safety should be notified as well. Supervisors should inform the employee that he/she may go to Employee Health Services (EHS).  A supervisor referral is not required. 
 
Employees who experience an injury or illness related to working with animals must report the event to their supervisor or PI and complete an Employee Accident Report. If medical treatment is needed, the employee should go to EHS or Student Health Services (SHS). If EHS or SHS is closed or emergency treatment is necessary, the employee should go to the Wexner Medical Center Emergency Department (or the nearest local emergency department if the employee is at a regional campus or outside of the Columbus, Ohio, area).
 
Contact information for these locations is provided below:
  • Employee Health Services, 201 McCampbell Hall, 1581 Dodd Drive  (614-293-8146)
  • Student Health Services, 1875 Millikin Road (614-292-4321)
  • Ohio State University Wexner Medical Center Emergency Department , 410 W. 10th Ave. (614-293-8333)
  • Wooster Campus, MEDPRO Group, 2201 Benden Drive (330-263-7270). During non-business hours, go to the Wooster Community Hospital, 1761 Beall Ave. (330-263-8100).
If an employee is exposed to a biohazard or recombinant DNA or bitten by a wild animal or USDA species, the Institutional Biosafety Committee (IBC) must be notified. IBC reporting requirements can be found on the IBC Policies webpage.

Any employee who is placed on restricted duty after a workplace accident must receive medical clearance prior to returning to work. If the employee is seen by a physician outside of EHS, the medical clearance must be provided to EHS for review before restrictions will be lifted.

Zoonotic fact sheets for fish

fishWhen working with animals, employees should be familiar with possible diseases that could be transferred between animals and humans. Below are a few causative agents that employees may be exposed to when working with fish:
  • Mycobacterium
  • Salmonella
  • Klebsiella
  • Cryptosporidium
  • Campylobacter 
Fact sheets with information about these specific agents, as well as agents for other species, are available on the Office of Environmental Health and Safety website. Check back frequently as fact sheets are being uploaded for other species. 

IACUC POLICIES

Policy updates

All policies developed by the Ohio State IACUC to assist investigators and staff with their research are available on the IACUC Policies webpage of the Office of Responsible Research Practices (ORRP) website. Policies and SOPs are reviewed on a regular basis to ensure that they continue to meet regulatory requirements.
 
Revised – Use of Pharmaceutical and Non-Pharmaceutical Grade Compounds in Animals and Labeling Expectations: This policy describes the regulatory requirements for investigators using pharmaceutical and non-pharmaceutical grade compounds. These compounds are specifically defined and aseptic preparation, appropriate storage and labeling expectations are addressed.
 
Regulations require the use of pharmaceutical grade compounds for injection in animals, even in acute procedures. Many experimental compounds used in research are not available as pharmaceutical grade (for example, agents obtained from Sigma or similar companies that require reconstitution). PBS is considered non-pharmaceutical as it is not intended for parenteral injection. When the use of non-pharmaceutical grade compounds is necessary, it must be listed in the animal use protocol and approved by the IACUC. 
 
When it is necessary to prepare and use an agent, researchers must ensure:
  • Aseptic preparation
  • Appropriate storage
  • Appropriate labeling 
View this revised policy on the Policies and Procedures webpage of the ORRP website. 
 
Revised – Euthanasia of Rodent Fetuses and Neonates: This policy was reviewed, definitions were added and the previous policy information was transferred to the new format for IACUC policies.

REMINDERS

IACUC semiannual inspections

Fall semiannual inspectionsThe IACUC will be performing semiannual inspections over the next several weeks. While many lab areas may have been visited by external site visitors during the recent AAALAC site visit and USDA inspection, facility inspections are required to be conducted semiannually by IACUC members from Ohio State.

Here are a few reminders that can help ensure records are complete and documentation is available for review:
  • Purple cards should be placed at the cage level, or a calendar can be used at the room level on the inside of the room door or in the room binder to document monitoring of special diet/water administration. It can be used for other purposes by PI staff. 
  • Yellow acetate placed at the cage level with an affixed white label provides documentation for animals receiving special husbandry procedures, and indicates the responsible party as University Laboratory Animal Resources (ULAR) or PI staff.
  • Housing logs document daily observations of animals, daily check of food and water supply, cleaning/sanitization of the feed/water bowls and environmental enrichment, daily recording of room temperatures, monthly humidity and bedding changes, if applicable.
  • Surgical records document the procedure performed, date and individual performing the surgery. Also records of anesthesia, surgery and post-operative care are maintained, including analgesic administration.
  • Anesthesia machines utilizing rebreathing and non-rebreathing circuits must be inspected annually and calibrated by a qualified vendor at least once every three years, unless otherwise indicated by the manufacturer. Documentation of the date for annual validation and calibration must be affixed to each vaporizer for review.
  • Charcoal/carbon filter canisters for the absorption of waste gases from the anesthesia scavenging system must be monitored. Documentation of the weight of the canister and a new canister should be used when the use limit is reached.
  • The label on the storage containers for drugs includes: the name of the compound(s) and diluent, final concentration and date of expiration.
  • Expired medical materials must be discarded in accordance with all relevant requirements or clearly labeled as “expired for acute terminal studies only” or “not for animal use” and stored in a separate location from materials used for animals and non-expired medical materials. Expired analgesics, sedatives, anesthetics and euthanasia solutions must not be used.
The IACUC thanks you for making progress toward improvements in the program and looks forward to seeing you during the semiannual inspections. Keep up the good work!

Revision to the Office of Research website

The Office of Research has removed the Research Online functionality on its website. If you have access to e-Protocol bookmarked through ResearchOnline, visit the Office of Research website for hyperlinks to access e-protocol, the IACUC webpage, the Office of the Attending Veterinarian webpage and more.

STAFF PROFILES

ORRP staff welcomes new IACUC/IBC analyst

Amber Camus joined the Office of Responsible Research Practices as an IACUC/IBC analyst in June. She assists researchers with their submissions, participates in educational outreach efforts and supports the operations of the Institutional Biosafety Committee and Institutional Animal Care and Use Committee. Prior to joining ORRP, Amber was a research associate in the Cognition and Language Lab in the Department of Psychology at Ohio State. She earned a BA in Ethnic Studies, Psychology and Women and Gender Studies from the University of Colorado and an MA in English from Ohio State.
IN THIS ISSUE
  • AAALAC site visit completed in June 2016
  • USDA inspection results
  • Employee accident reporting procedures
  • Zoonotic fact sheets for fish
  • Policy updates
  • Reminders
  • Staff profile
EVENTS

IACUC Meeting Dates

August 19, 2016
September 16, 2016
October 21, 2016
November 18, 2016

Meetings begin at
12:30 p.m.
 
Additional information about submission deadlines can be found on the IACUC meetings webpage.

ULAR training sessions

Facility Introduction and Mouse Overview

2016 dates and times:

August 11 (10 a.m.)
August 23 (1 p.m.)
September 8 (10 a.m.)
September 27 (1 p.m.)
October 13 (10 a.m.)
October 25 (1 p.m.)
November 10 (10 a.m.)
November 22 (1 p.m.)
 
Rodent Survival Surgery

2016 dates and times: 

August 16 (10 a.m.)
September 20 (10 a.m.)
October 18 (10 a.m.)
November 15 (10 a.m.)

Class sizes are limited to 15 registrants.
 
To register: Call 292-5094, email ulartraining or visit the research calendar.
 
Individual sessions may be arranged for protocol-specific techniques by completing the Training Request Form on the ULAR Training webpage and emailing it to the ULAR training coordinator at ulartraining@osu.edu.
RESOURCES

Office of
Research Units

© 2015 The Ohio State University – Office of Research
Office of Responsible Research Practices – Institutional Animal Care and Use Committee
Research Administration Building, 1960 Kenny Road, Columbus, OH 43210
Phone: 614-688-8457 | Fax: 614-688-0366 | Email the IACUC

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