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Spring 2015


Reminders for IACUC semiannual inspections

Based on findings from semiannual facility inspections, here are a few reminders that can help you:
  • Know the IACUC protocol: Personnel working with animals on an IACUC protocol should be familiar with the protocol and know what is approved in the protocol.
  • Watch for “protocol drift”: Protocol drift occurs when changes are implemented to the protocol without IACUC approval. To prevent this from occurring, be mindful of changes that need to be made to the protocol and ensure IACUC approval before implementation.  
  • Keep records up to date: Maintain accurate records of anesthesia, surgery and post-operative care, including analgesic administration. Also, maintain records for all equipment certifications, tests or maintenance (i.e., biosafety cabinet certification, autoclave validation, eyewash function checks and anesthetic vaporizer calibration). 
  • Check the lab for expired materials: Check expiration dates for all medical supplies and therapeutic agents, including diluents. If expired materials are kept for use, ensure the items are labeled as expired and segregate them from non-expired materials, or appropriately discard them in accordance with all relevant institutional, local, state and federal requirements. Expired medical materials that are not for animal use should be labeled as “not for animal use” and stored in a separate location from materials used for animals.  
  • Follow all lab safety procedures: Verify that all lab safety procedures are being followed, such as those pertaining to secured gas cylinders, controlled substances, sharps containers, etc.

Zoonotic fact sheets now available

When working with animals, it is important to be familiar with possible diseases that could be transferred between animals and humans. Fact sheets with information about specific agents for several agricultural species are available on the Office of Environmental Health and Safety website. Check back frequently as more fact sheets are being uploaded for other species.  

Successful USDA inspection

USDA logoRepresentatives from the United States Department of Agriculture (USDA) Animal and Plant Health Inspection Service conducted an unannounced inspection of housing facilities and animal use locations at the Ohio Agricultural Research and Development Center (OARDC) in Wooster in February. No compliance issues were identified during the inspection.


Laboratory Animal Science Professional Congratulations to Candace Hedrick and Stephanie Lewis for their publication, “A Novel Environmental Enrichment Distribution and Communication System for Large Animals" which appeared in the Laboratory Animal Science Professional (LAS Pro) magazine. The publication, which provides "Tech Tips" on new techniques and tactics, is a useful resource for members of the American Association for Laboratory Animal Science (AALAS).  



All policies developed by the Ohio State Institutional Animal Care and Use Committee are available on the IACUC Policies webpage of the Office of Responsible Research Practices (ORRP) website. These polices are reviewed on a regular basis to ensure that they meet regulatory requirements.

No current policies have been revised, nor have any new policies been created, since the last newsletter.


Personnel safety requirement reminder

Safety ReminderInvestigators are reminded that, in order to receive an IACUC approval letter for a protocol or amendment, all safety plans are required to be up to date. These include the chemical hygiene plan (CHP), institutional biosafety protocol and/or radioactive materials permit. ORRP, which provides administrative support to the IACUC, coordinates with the Office of Environmental Health and Safety (EH&S) to ensure that all required documents are completed; however, it is the investigator's responsibility to contact EH&S. To reduce the chance that IACUC protocol approval will be delayed, it is strongly encouraged that you contact your EH&S representative before submitting a new IACUC protocol or amendment to begin the review process. For more information, visit the Animal Research Safety webpage

Emergency eyewash stations

Eyewash StationsDuring semiannual inspections, the IACUC ensures that emergency eyewash stations are being checked on a weekly basis (as part of the oversight of the Occupational Health and Safety Program mandated as part of Animal Care and Use Programs). Environmental Health and Safety at Ohio State has provided guidance based on the American National Standard Institute (ANSI) standard Z358.1, which states that plumbed flushing equipment “shall be activated weekly for a period long enough to verify operation and ensure that flushing fluid is available.” The purpose of the weekly flush is to ensure there has not been an accumulation of rust or bacteria buildup in the stagnant water in the plumbing. Visit the EH&S website for a copy of the Emergency Eyewash Weekly Flushing SOP, which includes a flushing log that can be printed and posted near the eyewash station.

Investigator guidance resource

Remember that the IACUC provides additional information for researchers at Ohio State on the Investigator Guidance webpage. This resource includes information about best practices for housing of animals and templates for standard operating procedures and emergency plans that accompany a request for housing in non-ULAR investigator spaces; instructions and additional information on policies (such as Guidance for IACUC Policy on Movement of AnimalsHow to Prepare an Animal Use Protocol or How to Report Animal Numbers Manually); and information about alternatives to animal testing and research (such as information about assistance available for searching for alternatives and a fact sheet about the differences among various databases).


Renewal protocols

Please keep in mind that “renewal protocols” have to be reviewed as though they are new protocols. It is recommended that renewal protocols be forwarded for veterinary review two months (or sooner) from the expiration date.

Internet browser compatibility

One known issue with the e-Protocol system is non-compatibility with Internet Explorer 11. Internet Explorer 11 users may experience problems when attempting to edit text boxes within the e-Protocol form. If you are unable to edit text and can only view a "read only" webpage in your browser, try logging in to e-Protocol using an alternate browser, such as Mozilla Firefox, Google Chrome or Safari. 

Responding to changes requested

When responding to and making changes requested by a veterinarian or reviewer, remember that the change must be made in the body of the protocol document and not just in the reply box. Comments entered into the green reply boxes will disappear after the protocol is approved, so these responses will not be included in the final document.


ORRP welcomes new quality improvement specialist

Justin Lahmers joined the Office of Responsible Research Practices as a quality improvement specialist in January. Prior to joining ORRP, Justin was the staff training and development specialist for University Laboratory Animal Resources (ULAR), where he developed and implemented the animal husbandry staff training program. Justin has also worked in the Department of Animal Sciences as a beef cattle extension associate and was the herdsman at the Beef Center on the Columbus campus. Justin received his Registered Laboratory Animal Technologist (RLATG) certification from the American Association for Laboratory Animal Science. He earned his Bachelor of Science in Agriculture (with a double major in animal sciences and agribusiness) from Ohio State. 
  • Reminders for IACUC semiannual inspections
  • Zoonotic fact sheets
  • Successful USDA inspection
  • Congratulations
  • IACUC policies 
  • Reminders
  • e-Protocol tips
  • Staff profiles
Meeting planner

Upcoming IACUC meeting dates

April 17, 2015
May 15, 2015
June 19, 2015
July 17, 2015

Meetings begin at 12:30 p.m.

Additional information about submission deadlines can be found on the IACUC meetings webpage.

ULAR training sessions

Facility Introduction and Mouse Overview
April 9 (10 a.m.)
April 28 (1 p.m.)

May 14 (10 a.m.)
May 26 (1 p.m.)

June 11 (10 a.m.)
June 23 (1 p.m.)

July 9 (10 a.m.)

July 28 (1 p.m.)
Rodent Survival Surgery
April 21 (10 a.m.)
May 19 (10 a.m.)
June 16 (10 a.m.)
July 21 (10 a.m.)

ULAR training sessions are limited to 15 registrants.
To register: Call 292-5094, email ulartraining or visit the research calendar.
Individual sessions may be arranged for protocol-specific techniques by completing the Training Request Form on the ULAR training webpage and emailing it to the ULAR training coordinator at

Office of
Research Units

© 2015 The Ohio State University – Office of Research
Office of Responsible Research Practices – Institutional Animal Care and Use Committee
Research Administration Building, 1960 Kenny Road, Columbus, OH 43210
Phone: 614-688-8457 | Fax: 614-688-0366 | Email the IACUC

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