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October 2014

BY THE NUMBERS

Awards by Sponsor:
September 1, 2014, through September 30, 2014

SPONSOR NO. OF
AWARDS
AWARDS
AMOUNT
National Institutes of Health 63 $17,247,903
National Science Foundation 21 $5,123,520
Department of Education 12 $2,362,592
Department of Defense 19 $3,293,014
Department of Energy 9 $1,356,042
Department of Agriculture 31 $3,772,493
Department of Labor 1 $107,628
National Aeronautics and Space Administration 8 $773,249
Other Federal 21 $5,124,647
Total Federal 185 $39,161,088
Industry 189 $2,915,479
State of Ohio 6 $2,166,178
Private Agencies 32 $1,588,113
Colleges and Universities 1 $5,000
Other Non-Federal 2 $151,481
Total Non-Federal 230 $6,826,251
TOTAL 415 $45,987,339

THIS JUST IN...

Meet Ohio State's 2014 Innovators of the Year

As Ohio State continues to expand its role in the commercialization of research, it is important to create an environment that facilitates and rewards research creativity and entrepreneurship. To support and stimulate entrepreneurial activity among Ohio State researchers, three university-wide awards were presented on October 31, 2014, to three of the university's most successful entrepreneurs.
 
Innovator of the Year: Ali Rezai
 
The 2014 Innovator of the Year is Ali Rezai, MD, Stanley D. and Joan H. Ross Chair in Neuromodulation, director and CEO of the Ohio State Neurological Institute and director of the Ohio State Center for Neuromodulation. He is a world-renowned neurosurgeon who is in constant pursuit of new ways to end pain and suffering for patients living with disabilities. Rezai has spent his career developing technologies that regulate specific targets in the central nervous system to treat and alleviate the symptoms of a host of neurological disorders.

His research focuses on deep brain stimulation neural circuity, neurological sensors and monitors, and development of surgical tools and new neuromodulation approaches. Working with investigators from the Colleges of Medicine, Engineering and Arts and Sciences, Rezai initiated the first U.S. trials for deep brain stimulation to treat traumatic brain injury, Alzheimer's disease, alcoholism and obesity. In collaboration with engineers and scientists from Ohio State and Battelle, he implanted a microchip (Neurobridge) into a patient's brain that was linked to an external prosthetic sleeve. The procedure allowed the quadriplegic man to move his hand for the first time in four years using his thoughts. 
 
Rezai holds 35 issued U.S. patents and has more than 50 pending for medical devices and technologies. Three spin-off companies are based on his technology and scientific work – IntElect Medical, Autonomic Technologies and Cardionomics. He was named Cleveland Clinic Innovator of the Year in 2007 and Columbus Business First Innovator of the Year in 2011. 
 
Early Career Innovator of the Year: Kubilay Sertel
 
The 2014 Early Career Innovator of the Year is Kubilay Sertel, assistant professor of electrical and computer engineering. His research focuses on Terahertz-frequency sensing, imaging and communications. He developed and commercialized the first real-time, high sensitivity terahertz camera used for medical, communication and security applications.

Sertel developed the world's first video camera that "sees" in THz wavelengths. Unlike commercial optical cameras that capture light photons using semiconductor-based sensors, the much longer THz wavelengths use microscopic-scale antennas to capture THz power for detection.

Sertel’s camera has been commercialized by Traycer Systems Inc. Traycer has attracted over $7.5 million in venture-backed private equity and $3.5 million in supporting infrastructure.

 
He has one issued U.S. patent and two U.S. patents pending. He is principal investigator on a $6 million Multidisciplinary University Research Initiative (MURI) grant from the Office of Naval Research.
 
Sertel’s company, TeraProbes Inc., an Ohio State spin-off founded in 2014, recently received $100,000 in funding from the Ohio Third Frontier Technology Validation Start-up Fund to enable commercialization of an efficient method of testing next generation electronic chips.
 
Student Innovator of the Year: David Maung
 
The 2014 Student Innovator of the Year is David Maung, a doctoral student in the Department of Computer Science and Engineering. Maung was the chief architect and software developer for an at-home gaming program for stroke patients who experience motor weakness from hemiparesis – an inability to move one side of the body.
 
Recognizing the need for a low-cost, accessible therapy to improve arm function, Maung led the software development for “Recovery Rapids,” an innovative 3D computer-gaming version of contraint-induced movement therapy (CI) that provides in-home, high-repetition motor exercise that targets the affected hand, arm and shoulder and encourages use of the weaker arm to perform routine daily activities.
 
The software was developed in collaboration with a team of clinicians, computer scientists, an electrical engineer and a biochemist from the Department of Computer Science and Engineering, the Wexner Medical Center and Nationwide Children's Hospital. Next steps will be the formation of a corporation called "Games That Move You" to disseminate this therapy. 

RESEARCH NEWS

Making sense of big data for improved patient care

Ohio State is part of an 11-institution consortium to develop tools to make it easier to gather, analyze and interpret data generated by health sensors. The National Center of Excellence for Mobile Sensor Data-to-Knowledge (MD2K) will be established with a $10.8 million award from the National Institutes of Health (NIH). The MD2K team, led by the University of Memphis, will design novel big data solutions that will reliably quantify and interpret physical, biological, behavioral, social and environmental factors that contribute to health and disease risk. Researchers will apply new technologies to two health care challenges with high mortality rates: reducing hospital readmissions among congestive heart failure patients and preventing relapse among people who have quit smoking. At Ohio State, William Abraham, director of cardiovascular medicine at the Wexner Medical Center, will lead clinical studies of technologies developed for heart failure care. Emre Ertin, research assistant professor of electrical and computer engineering, who specializes in signal processing required to interpret sensor data, will design the novel biosensors. Clay Marsh, chief innovation officer for the Wexner Medical Center and professor of internal medicine, will direct the pursuit of health care innovations enabled by the center’s initial work.

New pharmaceuticals research facility to advance medical imaging

Cardinal Health and Ohio State opened the doors this month to the new Cardinal Health Translational Research Center for Molecular Imaging Pharmaceuticals, a central resource with the latest technology to advance the molecular imaging industry. Located at Ohio State’s Wright Center of Innovation in Biomedical Imaging in the Ohio State Research Park on west campus, the center will combine Ohio State’s research capabilities with Cardinal Health’s manufacturing and commercialization expertise for molecular imaging agents. Ohio State researchers will be able to create new molecular imaging agents in Positron Emission Tomography (PET imaging). As new imaging pharmaceuticals move through the drug approval pipeline, Cardinal Health will support their development, manufacturing and dispensing for clinical drug trials in Ohio and across its national network of radiopharmaceutical facilities. This one-stop-shop facility holds a radiopharmacy, state-of-the-art training center for nuclear pharmacists, a biomarker manufacturing facility and two cyclotrons.

Ohio Third Frontier invests in start-ups and innovation

Ohio State was awarded $2,200,000 from the Ohio Third Frontier Commission, in collaboration with Owens Corning, OMNOVA Solutions and Nanomaterial Innovation Ltd., to develop new insulating foams, a coating resin for manufacturing and a nano-paper for electromagnetic shielding. The award is part of the Innovation Platform Program which links the research capabilities of an already established technology platform at an Ohio university or nonprofit research institution to specific late-stage research, product development and innovation needs of Ohio for-profit companies. The Ohio Third Frontier Technology Validation and Start-up fund awarded KAir Battery LLC, based on an Ohio State technology, $50,000 to build a prototype battery aimed at the electric bike market. This fund supports protected technologies developed at Ohio research institutions that need known validation/proof that will directly impact and enhance their commercial viability and ability to support a start-up company.

Graduate students awarded Fulbright-Hays grants

Three Ohio State doctoral candidates have been awarded prestigious Fulbright-Hays Doctoral Dissertation Research Abroad grants for 2014-2015. Noah Dunham, anthropology, will study the feeding ecology and conservation of black and white colobus monkeys on the southern coast of Kenya to develop primate conservation strategies in the region. Heather Fair, evolution, ecology and organismal biology, will travel to Tibet and Hong Kong to research aquatic invertebrate biodiversity in glacier watersheds and create a bio-assessment method to protect water quality as water quantity dissipates over time due to climate change. Peter Tunkis, political science, will research the circumstances of elected parliamentarians changing political party affiliation in Poland and the Czech Republic to test his argument that the phenomenon is group-based rather than an individual decision.

Center for Retrovirus Research lands NCI grant

Experts at the College of Veterinary Medicine's Center for Retrovirus Research will study how cellular, microenvironmental and viral factors cooperate to promote development of cancer, thanks to an $8.6 million program project grant from the National Cancer Institute (NCI). The first phase of this multidisciplinary and multi-institutional study will use the center’s extensive knowledge of HTLV-1 to examine how specific RNA and proteins contribute to the survival and malignant transformation of human T-cell leukemia virus type 1. The goal is to find new diagnostic methods and treatment options for HTLV-1 infection and adult T-cell leukemia and related leukemia/lymphoma. Patrick Green, director of the Center for Retrovirus Research and professor in veterinary biosciences, is the principal investigator.

NEI funds convergence insufficiency study

The Convergence Insufficiency Treatment Trial (CITT) Investigator Group, of which Ohio State is a member, received an $8 million grant from the National Eye Institute (NEI) to study the effects of treatment for symptomatic convergence insufficiency (CI) on reading performance and attention. CI is a binocular vision disorder, impacting 5-10 percent of school-aged children. Symptoms include visual discomfort as well as a negative effect on reading performance. Marjean Kulp, professor of optometry, is the principal investigator for the Ohio State clinical center. The Data Coordinating Center for the study is also housed at the College of Optometry.

Urban geography researcher receives Van Cleef Medal

Edward Malecki, professor of geography, has been selected by the American Geographical Society (AGS) to receive the Van Cleef Memorial Medal. Named in honor of Eugene Van Cleef, professor emeritus of geography at Ohio State, the award recognizes scholars who have conducted outstanding research in the field of urban geography. The Van Cleef Memorial Medal has not been awarded since 1999. Malecki’s research focuses on urban, rural and regional economic development; technological change; regional policy; technology policy; telecommunications and corporation location and behavior. AGS, the oldest professional geographical organization in the U.S., is recognized as a pioneer in geographical research and education.

Furthering research in learning/memory disruption

Karl Obrietan, professor of neuroscience, received a $600,000 grant from the National Science Foundation (NSF) to investigate how the body’s circadian timing affects learning and memory. Circadian time-keeping mechanisms are found in all organ systems of the body. These mechanisms, regulated by a master pacemaker located within a small region of the brain called the suprachiasmatic nucleus (SCN), influence physiology, biochemistry and behavior. Disruption of circadian timing is associated with many neurological disorders including Alzheimer’s and Huntington’s disease. The researchers will study how cortical and SCN oscillators communicate, and how changes in time cues entrain the brain clock to disrupt cognition.

Advancing research on gallbladder infection

John Gunn, professor and vice chair of microbial infection and immunity, has received a grant of $617,000 from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases (NIAID) for his research into chronic infection of the gallbladder by antibiotic-resistant salmonella. Salmonella bacteria cause many diseases in humans and animals, including typhoid fever and gastroenteritis. Salmonella is also highly correlated with liver, gallbladder bile duct and pancreatic cancer. Researchers will study what enables the bacteria to colonize the gallbladder. They will also test therapeutics, including biofilm inhibitors and compounds to dissolve gallstones, which would release the bacteria, making them susceptible to conventional antibiotics.
 

FOCUS ON DISCOVERY THEMES

Studying the relationship between foods and health

The focus of the Center for Advanced Functional Foods Research and Entrepreneurship (CAFFRE) is on the relationship between diet and health - from crops to the clinic to the consumer. The center, part of the College of Food, Agricultural, and Environmental Sciences, involves faculty members from eight other colleges and schools, including the College of Medicine and the Comprehensive Cancer Center. Bringing together researchers from different disciplines has helped the team of 44 scientists garner $22 million in support since 2006, including $2 million from industry sponsors. This kind of interdisciplinary collaboration is at the heart of the Discovery Themes Initiative (DTI), which funded the teams' “Personalized Food and Nutritional Metabolic Profiling to Improve Health” proposal. Researchers will study the fingerprints of a person’s metabolome, or the complete big picture of thousands of biological and chemical compounds related to human metabolism, and correlate that with the person’s risk of disease. Steven Schwartz, Carl E. Haas Endowed Chair and professor of food science and technology, is the director of CAFFRE.

UPDATES

Important timeline for new Institutional Review Board submission system rollout

IRB Submit will go offline Nov. 11;
Buck-IRB will launch Nov. 17


Monday, November 17, 2014, will mark the launch of Buck-IRB, the university's new web-based electronic system for exempt and Institutional Review Board (IRB) submission and review. Buck-IRB is web-based and uses smart-form technology, which will streamline the application process. Research-related documents (consent forms and survey instruments) will also be uploaded and stored in the new electronic Buck-IRB system.

Buck-IRB will replace IRB Submit, the system currently in place. It is important to know that on November 11 at 12:01 a.m., IRB Submit will go offline. After this time, all submissions must be held and entered in the new Buck-IRB system which will go “live” at 6 a.m. on November 17th. Materials already in the IRB Submit queue will be routed for signature and reviewed under current procedures. Investigators with currently approved studies will be asked to enter basic study information (e.g., participant population, recruitment numbers) into the new system at the time of the first amendment or continuing review. New studies can be entered directly into the system without this migration step.

In order to make this transition as easy as possible for everyone, it is recommended that between now and the November 17th launch of Buck-IRB, materials be submitted via the current IRB Submit system only as necessary (i.e., to avoid protocol expiration or to report unanticipated problems). 

A new Buck-IRB webpage has been created to provide additional information about the system, including upcoming training sessions, user guides and instructions, and answers to frequently asked questions. Please check this page for updated information as the launch date approaches. For questions or to request a training session, please contact Susan Ebert, e-IRB program director, at 614-292-0184 or ebert.55@osu.edu.

Research Commons
seeking faculty, grad
student input

In anticipation of the opening of the new Research Commons space in January 2016, University Libraries has launched a survey to gauge the research habits and goals of faculty and graduate students. The Research Commons currently offers virtual support for faculty and graduate students, providing training and tools to assist in the planning and conduct of research at Ohio State. The opening of the Research Commons in the 18th Avenue Library will provide a dedicated location where faculty and graduate students can access a variety of services to support their research, from finding funding, to connecting with experts or collaborators, to publication. 

Faculty Survey
Graduate/Doctoral Candidate Survey
EVENTS

Mathematics and Music: The Beauties in Pattern

November 2, 2014
3-4 p.m. (Lecture)
4-5 p.m. (Reception)
Wexner Film/Video Theater

James Sneyd, professor of mathematics, University of Auckland, Royal Society of New Zealand

New James Faculty, Staff
and Student Open House

November 5, 2014
460 W. 10th Avenue

Be one of the first to discover why the new James Cancer Hospital and Solove Research Institute, opening in December, is the world’s most advanced cancer hospital. Faculty, staff and students are invited to take a tour and enjoy refreshments. Tours occur at 6-8 a.m., 11 a.m.-2 p.m. and 6-8 p.m. 
 

Dorothy M. Davis Heart and Lung Institute Research Day

November 5, 2014
8:30 a.m.-3:45 p.m.
First floor Biomedical Research Tower (BRT)
460 West 12th Avenue

Environmental Professionals Network Breakfast Club

Unmanned Aerial Vehicles: Environmental and Ag Applications Take Flight 
November 12, 2014
7:15-9:15 a.m.
Nationwide and Ohio Farm Bureau 4-H Center

Provost's Discovery Themes Lecturer Program

Technology and Self
November 20, 2014
5:30-6:30 p.m.
Archie M. Griffin Ballroom
Ohio Union

Lecturer: Sherry Turkle, Abby Rockefeller Mauzé
Professor of the Social Studies of Science and Technology; Program in Science, Technology, and Society; MIT

Health Sciences Innovations Conference and Trade Show

Taj Mahal Palace Hotel
Mumbai, India
 
The conference is sponsored by Ohio State and the All India Institute for Medical Sciences. Contact: Brent Toto.
OPPORTUNITIES & ANNOUNCEMENTS

Battelle Engineering, Technology and Human Affairs (BETHA) Endowment

Call for Proposals
Deadline: November 25, 2014

 

Inspiring Female Entrepreneurs at Ohio State and Beyond

Professional Development Opportunity
Applications Due: 
November 10, 2014


REACH for Commercialization 2015, offered by Gender Initiatives in STEMM, is a series of four workshops designed to help women faculty explore commercialization as a means of expanding the impact of their research. 

Edward F. Hayes Graduate Research Forum

Call for Abstracts
Deadline: November 14, 2014

The Edward F. Hayes Graduate Research Forum showcases the innovative and exemplary research being conducted by graduate students across the full range of graduate degree programs. Cash prizes will be awarded to top-judged presentations in each academic area. The Hayes Forum will take place on February 20, 2015. 

NIH Follow that Cell Challenge

Funding Opportunity
Deadline: December 15, 2014 (Phase 1)

The National Institutes of Health (NIH) is challenging science innovators to compete for prizes totaling up to $500,000, by developing new ways to track the health status of a single cell in complex tissue over time.

Schottenstein Prize in Cardiovascular Sciences

Funding Opportunity
The Ohio State University Wexner Medical Center’s Ross Heart Hospital is accepting applications for the 2015 Jay and Jeanie Schottenstein Prize in Cardiovascular Sciences. The Schottenstein Prize, among the largest monetary prizes in the U.S. dedicated to cardiovascular research, is awarded biennially to an international leader in the clinical sciences of cardiovascular medicine, cardiothoracic surgery or the basic sciences of molecular or cellular cardiology. The recipient will receive a $100,000 honorarium to fund their research.
 

U.S. EPA 12th Annual P3 Awards

Funding Opportunity
The U.S. Environmental Protection Agency (EPA) is sponsoring a National Student Design Competition for Sustainability Focusing on People, Prosperity and the Planet (P3). The program supports science-based projects and designs developed by interdisciplinary student teams that improve quality of life, promote prosperity by developing local economies and protect the planet by conserving resources and minimizing pollution. Awards up to $15,000 will made for Phase I grants, and up to $75,000 for Phase II grants. 
 

Young Investigator Grant for Probiotics Research

Funding Opportunity
The Global Probiotics Council (GPC) is offering three $50,000 Young Investigator Grants for Probiotics Research (YIGPRO) to support new research on probiotics and gastrointestinal microbiota in the U.S. Young investigators interested in understanding the health benefits of probiotics and microbiota and the relationship between probiotics, gastrointestinal microbiota and the body are invited to apply.

 

Undergraduate Research Scholar Award

Funding Opportunity
 
Are you an undergraduate student interested in pursuing your first faculty-supervised research project or creative activity? If so, you can apply for a $1,000 Undergraduate Research Scholar award to get your project started. Applications are accepted year-round, on or before the first of each month.
Did you know? 
The Institute for Materials Research (IMR) has added the Semiconductor Epitaxy and Analysis Laboratory (SEAL) to its cadre of
IMR-supported facilities

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208 Bricker Hall, 190 North Oval Mall, Columbus, OH 43210
Phone: 614-292-1582 | Fax: 614-292-6602 | Email the Office of Research

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