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A Snapshot of Happenings at the SEBM for Frederick Domann
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PRESIDENT'S MESSAGE | WARREN ZIMMER

Greetings,
 
As we approach 2016 Experimental Biology Meeting in San Diego, I want to call your attention to several of the events we have planned for the meeting.  First, in this issue of Explorations we list the recipients of the SEBM Young Investigator Awards for 2016 and I want to invite everyone to attend the SEBM Social (Sunday TIME and PLACE), where each of these outstanding young scientist will present a “Flash Chat” describing their research.  Additionally, we have listed their presentation times and place during the meeting and I strongly encourage all of our members present at EB to visit their posters as I’m certain we all will be stimulated by their poise and knowledge, possibly learning a thing or two.  At the Social we will also be acknowledging the Best Paper Awards, presenting the 2016 Distinguished Scientist, and honoring individuals who have served the society on council and committees.

Equally as inspiring as our 2016 Young Investigator Awardees is our speakers at upcoming symposia, scientific sessions and meetings.  On Sunday of EB our annual symposia entitled “Translational Scientist: Integrating Science and Medicine” will feature Dr. Ken Ramos, Associate Vice-President of Precision Health Sciences, Director MD-PhD Program University of Arizona College of Medicine Tucson, emphasizing the role of the NIH in driving the training of the healthcare workforce and advocating collaborative science; Dr. Michael Friedlander, Executive Director, Virginia Tech Carilion Research Institute, Associate Provost for Health Sciences and Senior Dean for Research, Virginia Tech Carilion School of Medicine, speaking on new and innovative approaches in medical education driving collaborative learning of clinical scientist; and Dr. Michael Wood, Licensing and Collaboration Director, AstraZeneca Neuroscience, articulating innovative approaches to forge new interactions between academic, industry, and clinical partners to continue moving health care through collaboration and discovery. Additionally on the topic of training the healthcare workforce, SEBM will co-sponsor with ASBMB a special lecture by Dr. Francis Collins, Director NIH, entitled “Everything that matters in biomedicine builds on basic science” on Tuesday April 5 at EB.   On Monday at EB Drs. Steve Goodman and Betty Pace have organized the session “Sickle Cell Severity” bringing together world experts in the study of sickle cell on the dais.  Finally, President-Elect Dr. Peter Stambrook has put the finishing touches on the program for 2016 IEBMC meeting in Chengdu, China  with focus upon Single Cell Analyses in Disease by confirming Dr. John Gurdon, Nobel Laureate 2012 in Physiology and Medicine as the keynote speaker.  I am personally excited about learning from all these world leaders and I invite all to save the dates to attend these stimulating sessions/meetings.  We are also interested in soliciting your input on content of future symposia and meetings, so feel free to contact the office ed@sebm.org or any of the councilors and let us know your thoughts.

To close, I want to again extend an invitation for members to take a minute and let us know what is happening in your sphere.  Please scroll down and click on the member survey and let us help with networking, career development or camaraderie.



Warren Zimmer
President, SEBM

SEBM 2016 AWARD WINNERS


YOUNG INVESTIGATOR AWARDEES

Steven Brooks, West Virginia University
Pharmacological Inhibition of NAD(P)H Oxidase with the Peptide gp91ds-tat During Ischemic Stroke Reduces Infarct Volume and Improves Vascular Reactivity in Obese Zucker Rats
Poster Session Title: Novel Mechanisms of Cerebrovascular Dysfunction
Day of presentation: Monday, April 4, 2016
Poster Board Number: B99
Poster Presentation Time: 12:45 PM - 3:00 PM
Location: San Diego Convention Center, Exhibit Halls A-D

Sarika Chaudhari, Govt. Medical College, Nagpur, India
Store Operated Ca2+ Entry Suppressed TGF&[beta]1- Smad3 Signaling Pathway in Glomerular Mesangial Cells
Poster Session Title: Ion Channels, Transporters and Pumps in Health and Disease
Day of presentation: Tuesday, April 5, 2016
Poster Board Number: B241
Poster Presentation Time: 12:45 PM - 3:00 PM
Location: San Diego Convention Center, Exhibit Halls A-D

Karen Doersch, Texas A&M Health Science Center College of Medicine
Wound Healing in a Model of Systemic Lupus Erythematosus may be Delayed by a Lack of Interleukin-2
Poster Session Title: Epithelial Barriers, Cell Migration and Tissue Repair
Day of presentation: Monday, April 4, 2016
Poster Board Number: A221
Authors must be present at their posters from* 11:45 AM - 1:45 PM
Location: San Diego Convention Center, Exhibit Halls A-D
Rachel Fenske, University of Wisconsin - Madison
Loss of the inhibitory G-protein, Gz, protects against Type I Diabetes-like hyperglycemia by stimulating islet signaling pathways that promote beta-cell function and survival
Poster Session Title: Cell Signaling: Proteins, Pathways, and Mechanisms
Day of presentation: Monday, April 4, 2016
Poster Board Number: B322
Poster Presentation Time: 12:45 PM - 3:00 PM
Location: San Diego Convention Center, Exhibit Halls A-D

Kuan-Hsun Huang, Pennsylvania State University
Lipid Emulsions, Rich in n-3 or n-9 Fatty Acids, Reverse the Progression of Parenteral Nutrition-Induced Hepatic Steatosis in Mice
Poster Session Title: ASN Emerging Leaders in Nutrition Science Poster Competition
Day of presentation: Saturday, April 2, 2016
Location: San Diego Convention Center, Sails Pavilion



Vasundhara Kain, University of Alabama At Birmingham
Resolution Agonist 15-epi-Lipoxin A4 Directs FPR2 to Expedite Healing Phase Post-Myocardial Infarction
Session Title: Mechanisms of Myocardial Failure and Fibrosis
Day of Presentation: Monday, April 4, 2016
Presentation Start Time: 2:25 PM
Presentation End Time: 2:40 PM
Program Number: 306.2
Location: San Diego Convention Center, Room 5A

Trinity Kronk, Emory University
Interleukin-6 Receptor Alpha Exhibits Differential Cellular Localization Within the Nephron
Day of presentation: Sunday, April 3, 2016
Poster Presentation Time: 8:00 PM
Location: San Diego Marriott Marquis & Marina, Presidio




Gilberto Moralez, UNT Health Science Center
Centrally Acting Perindopril Attenuates the Exercise Induced Increase in Muscle Sympathetic Nerve Activity during Heavy Dynamic Exercise
Poster Session Title: Autonomic Adjustments to Exercise
Day of presentation: Monday, April 4, 2016
Poster Board Number: B502
Poster Presentation Time: 12:45 PM - 3:00 PM
Location: San Diego Convention Center, Exhibit Halls A-D


Van Ninh, Louisiana State University Health Science Center
Lysyl Oxidase Inhibition Alleviates Fibrosis and Dysfunction in Rodents with Established Cardiac Disease
Poster Session Title: Extracellular Matrix/Cardiac Remodeling
Day of presentation: Tuesday, April 5, 2016
Poster Board Number: B29
Poster Presentation Time: 12:45 PM - 3:00 PM
Location: San Diego Convention Center, Exhibit Halls A-D


Jillian Noblet, Indiana University School of Medicine
Role of leptin in coronary vascular dysfunction and proliferation
Poster Session Title: Coronary Circulation
Day of presentation: Sunday, April 3, 2016
Poster Board Number: B109
Poster Presentation Time: 12:45 PM - 3:00 PM
Location: San Diego Convention Center, Exhibit Halls A-D



Stacey Rodenbeck, Indiana University School of Medicine
SERCA inhibition attenuates medial thickening in an organ culture model of coronary artery disease
Poster Session Title: Coronary Circulation
Day of presentation: Sunday, April 3, 2016
Program Number: 733.9
Poster Board Number: B117
Poster Presentation Time: 12:45 PM - 3:00 PM
Location: San Diego Convention Center, Exhibit Halls A-D

Cynthia Tchio, Morehouse School of Medicine
Leptin Regulation of HDAC and miRNA affect Pancreatic Cancer Stem Cells
Day of presentation: Sunday, April 3, 2016
Poster Presentation Time: 8:00 PM
Location: San Diego Marriott Marquis & Marina, Presidio





 

DISTINGUISHED SCIENTIST AWARD


Frederick Domann, PhD
The University of Iowa

Councilor, SEBM Member Since 1991
Dr. Domann pursues this objective in the context of cancer to examine how abnormal redox biology and metabolism contribute to loss of epigenetic control of normal gene expression during cancer progression.


Farzin Farzaneh, PhD
King's College London
 
International Councilor, SEBM Member Since 2008
Dr. Farzanaeh has over 25 years research experience in tumor immunology, cancer cell biology and cancer gene therapy. The development of novel immunotherapeutic approaches for the treatment of high-risk patients with acute myeloid leukemia (AML) has been an area of intensive study in the Farzaneh group.

Michael Friedlander, PhD
Virginia Tech Carilion Research Institute

Past President, SEBM Member Since 2006
Dr. Friedlander's research program is directed at understanding the cellular and molecular processes that underlie adaptive changes in synaptic networks in the brain, specifically those that regulate alterations in synaptic efficiency between neurons within the cerebral cortex.

H. Rex Gaskins, PhD
Institute for Genomic Biology, University of Illinois/Urbana-Champaign

Past President, Member of SEBM Since 1989
Dr. Gaskins' laboratory focuses on microbial sulfur metabolism as it pertains colorectal cancer and contributions of glutathione and redox homeostasis to cancer cell metabolism.



BEST PAPER AWARDS

Experimental Biology in Basic Research
Ke Liang, Xue-qin Ding, Chen Lin, and Y James Kang
Featured Article: Hypoxia-inducible factor-1α dependent nuclear entry of factor inhibiting HIF-1 
Exp Biol Med (Maywood) November 2015 240: 1446-1451, first published on February 16, 2015 doi:10.1177/153537021557082

Burt Sobel Award for Clinical/Preclinical and Translational Research 
Laurent-Emmanuel Monfoulet, Claire Philippe, Sylvie Mercier, Véronique Coxam, and Yohann Wittrant
Featured Article: Deficiency of G-protein coupled receptor 40, a lipid-activated receptor, heightens in vitro- and in vivo-induced murine osteoarthritis 
Exp Biol Med (Maywood) July 2015 240: 854-866, first published on January 13, 2015 doi:10.1177/1535370214565078

Alan MacDiarmid Award for Interdisciplinary Research
Lars C Huber, Silvia Ulrich, Caroline Leuenberger, Max Gassmann, Johannes Vogel, Leonardo Glutz von Blotzheim, Rudolf Speich, Malcolm Kohler, and Matthias Brock
Featured Article: microRNA-125a in pulmonary hypertension: Regulator of a proliferative phenotype of endothelial cells 
Exp Biol Med (Maywood) December 2015 240: 1580-1589, first published on April 7, 2015 doi:10.1177/1535370215579018
 
FASEB HILL DAY
TOM THOMPSON, SEBM REPRESENTATIVE TO FASEB 
 
On March 2nd-3rd I traveled to Washington D.C. to advocate for biological and biomedical research. The event was hosted by FASEB and included approximately 45 representatives for its various organizations and board members. We kicked off the meeting by honoring Rep. Tom Cole and Sen. Roy Blunt, Chairmen of the House and Senate Appropriations Subcommittees on Labor, Health and Human Service, and Education Related Agencies, for their roles in securing a $2 billion budget increase for NIH. Even more encouraging was that each acknowledged continued support to the NIH with future budget increases.

The following day we dispersed into smaller groups in order to meet with Senators and Representatives, and their staff members, from our home states. Here we relayed a consistent message to increase funding to the NIH by an additional $3 billion for the following fiscal year, and also, that sustained and dependable growth is the key to the long-term success of the NIH, NSF and our scientific community. In general, I felt the overall sentiment was positive and there seemed to be bi-partisan support and recognition that funding to the NIH should be a National priority. If possible, I would encourage society members to reach out to their Senators or Representatives and advocate for NIH funding.

2016 ANNUAL MEETING EVENTS
April 2-6, San Diego, CA


SEBM events are held in conjunction with the Experimental Biology meeting.  Registration is required, and your registration for Experimental Biology includes access to hundreds of scientific sessions, social functions and networking events.



The Translational Scientist: Integrating Science and Medicine
April 3, 4:00PM – 6:15PM
San Diego Convention Center, Room 1A


The 2016 SEBM Symposium, “Translational Scientist: Integrating Science and Medicine”, will focus on key concepts of the translation of discovery to health care.
 
  • Dr. Ken Ramos – University of Arizona Health Sciences, Current State of Physician Scientist Training
  • Dr. Michael Friedlander – Virginia Tech Carilion Research Institute, New Approaches in Medical Training of Health Researchers
  • Dr. Michael Wood – AstraZeneca Neuroscience, Forging Academia/Industry Partnerships that Transform Discoveries into Treatments

Awards Reception and Career Roundtable
April 3, 7:00PM 
San Diego Marriott Marquis & Marina, Presidio

 
Join us to celebrate this year's awards winners and have a discussion with senior scientists about career options.
 
Meet the Editor-in-Chief of Experimental Biology and Medicine, Steven R. Goodman 
April 4, 10:00 am
SAGE booth #1906

 
Come along to talk to the Editor-in-Chief of SEBM’s official journal. Find out more about the journal, including key upcoming papers and special issues. You can also discuss submitting your next paper to EBM and learn about the author benefits we offer.
 
Scientific Session: Focus on Sickle Cell 
April 4, 3:00PM – 5:30PM
San Diego Convention Center, Room 6A

 
This Symposium will provide the audience with the current understanding of the molecular bases for the variability of sickle cell severity and current treatment for SCD patients.
 
  • Charles Quinn, MD,  – Cincinnati Children's Medical Hospital Center,  “Clinical severity in sickle cell disease: definitions and prognostication”
  • Vivien Sheehan, MD/PhD, –  Baylor College of Medicine, Children's "Rheological Abnormalities of Pediatric Hemoglobin SC Patients"
  • Martin Steinberg, MD,  – Boston University School of Medicine, “Genetic Basis of HbF Variability in Sickle Cell Anemia; A Global Perspective”
  • Winfred Wang, MD,  –  St. Jude Children's Research Hospital, “Is Hydroxyurea Efficacious in Both Severe and Non-Severe Sickle Cell Disease?”
 
 
RENEW YOUR SEBM MEMBERSHIP

It is an exciting time to be an SEBM member, and we want to make sure you're included in our bright future.  Renewal is now available for 2016.  Renew now to receive undistributed service in your member benefits! 
 
MEMBERSHIP SURVEY

Do you have feedback for us?  We'd love to get your thoughts on how the Society's doing and how we can better serve your needs.  Take just a few minutes to complete our 6 question member survey!

CONNECT AT SEBM.ORG

Log-in to the SEBM members-only community area for collaborative discussions, where you can build a profile, upload a photo and connect with your colleagues. We invite you to explore your new space today!
 
2016 SEBM ANNUAL MEETING

In Conjunction with Experimental Biology 
April 2-6
San Diego, CA
http://www.sebm.org/annual-meeting
 
FOLLOW US ON TWITTER

To keep up-to-date on SEBM happening between issues of Explorations, follow us on twitter. Also featuring content from Experimental Biology and Medicine.
Sickle Cell Session at EB

SEBM will be hosting a scientific session this year at Experimental Biology this year on Monday, April 4th.  Stay tuned for details.
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