Specialized DART Necropsy Support
DART training is focused primarily on the recognition of skeletal abnormalities (e.g., the presence or absence of ossification), bone morphometry (measured length and area), relationships between bones, abnormal bone fusion, and the presence of additional bony structures or sutures, in Day 21 rat fetuses and Day 29 rabbit fetuses. Handling, restraint, sex determination, euthanasia protocols, and C-sectioning methods were reviewed for each species, in addition to fetal external examination procedures and the appropriate use of gross lesion descriptions.
Founded in 1971, Experimental Pathology Laboratories, Inc. (EPL®) is a private, employee-owned U.S. company that is recognized internationally for its ability to meet the needs of the scientific community and the challenges of preclinical safety testing with high quality, on-time histopathology services. Valued for its objectivity and responsiveness, EPL has become industry’s and government’s premier source for expert toxicologic pathology evaluation and consultation.
EPL’s staff regularly publishes relevant new information in peer-reviewed scientific journals and shares their expertise through presentations pertaining the impact of histology on regulatory concerns and drug development at scientific meetings and other events.