CHIC bi-monthly newsletter
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First year outputs! 

The first year reporting has just been concluded with the summary of the activities performed by the consortium and of the achieved outputs which will be the base for the annual review taking place in September 2014. The reporting shows a high level of activities from all WPs and partners with 10 high quality deliverables submitted to the EC. This is also represented by more than 60 dissemination events and publications related to the CHIC project results. This is an extract on the first year publications: 
  • “Computational Delineation of Tyrosyl-Substrate Recognition and Catalytic Landscapes in the Epidermal Growth Factor Receptor Tyrosine Kinase Domain”, by Y Liu, in Molecular Biosystems, 10(7):1890-904, doi: 10.1039/c3mb70620f, 2014.
  • “Mesoscale computational methods for membrane remodeling by curvature inducing proteins”, by N Ramakrishnan, and PB Sunil, in Physics Reports, in press, 2014.
  • “Enabling multiscale modeling in systems medicine”, by O Wolkenhauer, C Auffray, O Brass, J Clairambault, A Deutsch, D Drasdo, F Gervasio, L Preziosi, P Maini, A Marciniak-Czochra, C Kossow, L Kuepfer, K Rateitschak, I Ramis-Conde, B Ribba, A Schuppert, R Smallwood, F Winter, and H Byrne, in Genome Medicine, 6:21, 2014.
  • “The Technologically Integrated Oncosimulator: combining multiscale cancer modelling with information technology in the in silico oncology context”, by D Dionysiou, A. Lunzer, R. Belleman, E. Kolokotroni, E. Georgiadi, M. Erdt, J. Pukacki, S. Rueping, S. Giatili, A. Donofrio, S. Sfakianakis, K. Marias, C. Desmedt, M. Tsiknakis, N. Graf, in IEEE J. Biomed Health Inform, 18(3):840-54, doi: 10.1109/JBHI.2013.2284276, 2014.
  • “Dendritic cell vaccination for glioblastoma multiforme: review with focus on predictive factors for treatment response”, by J Dejaegher, and S De Vleeschouwer, in Immuno Targets and Therapy, 3:55-66, doi:10.2147/ITT.S40121, 2014
  • “The Virtual Skeleton Database: An Open Access Repository for Biomedical Research and Collaboration”, by M Kistler, S Bonaretti, M Pfahrer, and R Niklaus, in Journal of Medical Internet Research, 15(11): e245, doi: 10.2196/jmir.2930, 2013.
  • “Computational Methodology for Mechanistic Profiling of Kinase Domain Mutations in Cancers”, by PJ Huwe, in Proceedings of the IEEE, 5th International Advanced Research Workshop on In Silico Oncology and Cancer Investigation, 2013.
  • “In Silico Oncology: Exploiting Clinical Studies to Clinically Adapt and Validate Multiscale Oncosimulators”, by D Dionysiou, A Lunzer, R Belleman, E Kolokotroni, E Georgiadi, M Erdt, J Pukacki, S Rueping, S Giatili, A d'Onofrio, S Sfakianakis, K Marias, C Desmedt, M Tsiknakis, and N Graf, in Conf Proc IEEE Eng Med Biol Soc, 5545-9, doi: 10.1109/EMBC.2013.6610806, 2013.
  • “The Technologically Integrated Oncosimulator: Combining Multiscale Cancer Modeling with Information Technology in the In Silico Oncology Context”, by D Dionysiou, A Lunzer, R Belleman, E Kolokotroni, E Georgiadi, M Erdt, J Pukacki, S Rueping, S Giatili, A d'Onofrio, S Sfakianakis, K Marias, C Desmedt, M Tsiknakis, and N Graf, in J Biomed Health Inform, 18(3):840-54, doi: 10.1109/JBHI.2013.2284276, 2013.
  • “Molecular modeling of ErbB4/HER4 kinase in the context of the HER4 signaling network helps rationalize the effects of clinically identified HER4 somatic mutations on the cell phenotype”, by SE Telesco, R Vadigepalli, R Radhakrishnan, in Biotechnology Journal, 8(12):1452–1464, doi: 10.1002/biot.201300022, 2013.
  • “Multiscale Cancer Modeling and In Silico Oncology: Emerging Computational Frontiers in Basic and Translational Cancer Research”, by N Graf, and R Radhakrishnan, in J Bioengineer & Biomedical Sci, 3(2):e114, doi: 10.4172/2155-9538.1000e114, 2013.
  • “Functional tissue units and their primary tissue motifs in multi-scale physiology”, by P Grenon, R Baldock, and P Hunter, in Biomed Semant, 4:1, doi: 10.1186/2041-1480-4-22, 2013.

News from CHIC

  • Partner ICCS will organize the workshop “Multiscale modelling of cancer” at the 3rd Virtual Physiological Human Conference 2014, which will be held on September 9-12, 2014 at Trondheim, Norway. The programme of the conference, in which the workshop is included, is available at
  • CHIC project annual review meeting will take place on the 3rd of September 2014 in Brussels.
  • CHIC general assembly will take place in Leuven in October 2014. Details will follow in advance of the meeting. 

News from the VPH community

  • VPH-Share hands-on demonstration at VPH2014 which will be held on September 12th, 2014 in Trondheim, Norway. See the programme of the conference for more information.
  • Health priorities of the Italian presidency of the EU Council: The priorities in the field of healthcare of the next Presidency of the Council of the European Union will be held by Italy during the second Semester of 2014. Read more 
  • European Commission promotes open access to scientific data: The European Commission on 26 June 2014 announced that it would be seeking ways to initiate “Science 2.0”, whereby researchers would be encouraged to take part in data sharing, avoiding duplication and improving accessibility to crucial research results. Read more 

Forthcoming events

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